Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Skin Cancer

Skin Cancer

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise.
Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own EpiSCs...

Healing II: Complications

Healing II: Complications

Complications during healing arise when tissue repair is altered by local or systemic factors. These changes involve abnormal collagen deposition, altered biomechanics, and reduced vascular supply, impairing restoration of normal structure and function.Loss of FunctionScar tissue differs significantly from the original tissue it replaces. In the skin, fibrosis lacks adnexal structures such as hair follicles, sebaceous glands, and sweat glands. Their absence reduces tactile sensitivity, impairs...

Skin Diseases and Disorders

Skin Diseases and Disorders

Skin is the first line of defense and encounters a variety of microbes. Some pathogenic strains are often the cause of a broad range of infections of the skin and other body systems. These conditions can affect people of all ages and may have different causes, including genetic factors, infections, autoimmune reactions, environmental factors, and lifestyle choices.
Gram-positive Staphylococcus spp. and Streptococcus spp. are responsible for many of the most common skin infections. However, many...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Presence of fetal intervillous cells in a case of chronic placental inflammation.

Journal of reproductive immunology·2025

Same author

Real-world EGFR testing practices for non-small-cell lung cancer by thoracic pathology laboratories across Europe.

ESMO open·2023

Same author

Wrist fusion in peripheral paralysis.

Hand surgery & rehabilitation·2021

Same author

Management of complex forearm defects: A multidisciplinary approach.

Annales de chirurgie plastique et esthetique·2020

Same author

Coverage of cutaneous substance loss in the leg: Techniques and indications.

Annales de chirurgie plastique et esthetique·2020

Same author

Aesthetic functional reconstruction of the mutilated hand: Indications and selection of reconstructive techniques.

Annales de chirurgie plastique et esthetique·2020

Same journal

Contribution to surgical education: Development of a website dedicated to perforator flaps of the upper limb.

Annales de chirurgie plastique et esthetique·2026

Same journal

Superficial craniofacial arteriovenous malformations: A report of six cases and review of treatment modalities.

Annales de chirurgie plastique et esthetique·2026

Same journal

Global research trends andintellectual structure of genioplasty: A 45-year bibliometric analysis (1980-2025).

Annales de chirurgie plastique et esthetique·2026

Same journal

Dermal substitutes in keloid surgery: A systematic review and analysis of 116 lesions.

Annales de chirurgie plastique et esthetique·2026

Same journal

Surgical approaches for prosthesis placement in transgender patients: A narrative review.

Annales de chirurgie plastique et esthetique·2026

Same journal

Kiss flap in middle leg reconstruction: A technical note.

Annales de chirurgie plastique et esthetique·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Jun 10, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Published on: July 28, 2023

[Spontaneous keloids: about a rare case].

N Kerfant¹, P Gasnier, A Boloorchi

¹Service de chirurgie plastique, reconstructrice et esthétique, CHU de La-Cavale-Blanche, Brest, France. nathalie.kerfant@chu-brest.fr

Annales De Chirurgie Plastique Et Esthetique

|July 29, 2010

Summary

This summary is machine-generated.

This case study discusses spontaneous keloids, rare in Caucasian individuals, appearing without injury. It reviews literature and therapeutic strategies for these unusual skin lesions.

More Related Videos

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

Published on: November 29, 2024

Related Experiment Videos

Last Updated: Jun 10, 2026

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Isolation, Culture, and Characterization of Primary Dermal Fibroblasts from Human Keloid Tissue

Published on: July 28, 2023

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

A Mouse Model of Mechanotransduction-driven, Human-like Hypertrophic Scarring

Published on: November 29, 2024

Area of Science:

Dermatology
Pathophysiology
Clinical Case Study

Background:

Keloids are benign fibroproliferative dermatological conditions.
They typically arise after skin injury, but spontaneous occurrence is rare.
Understanding the pathophysiology of spontaneous keloids is crucial for effective treatment.

Observation:

A 21-year-old Caucasian female presented with multiple keloids on her back and chest.
These lesions developed spontaneously, without any history of trauma, dermatological disease, or surgery.
The presentation is unusual, particularly given the patient's ethnicity.

Findings:

Spontaneous keloids are infrequently documented in Caucasian populations.
The exact mechanisms driving spontaneous keloid formation remain largely unknown.
This case highlights the variability in keloid presentation and etiology.

Implications:

Further research into the pathophysiology of spontaneous keloids is warranted.
This case may inform diagnostic approaches for unexplained keloid formation.
A review of current and potential therapeutic strategies is essential for patient management.