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Updated: Jun 10, 2026

Integrated Photoacoustic Ophthalmoscopy and Spectral-domain Optical Coherence Tomography
Published on: January 15, 2013
Label-free photoacoustic ophthalmic angiography
Song Hu1, Bin Rao, Konstantin Maslov
1Department of Biomedical Engineering, Washington University in St. Louis, St. Louis, Missouri 63130, USA.
Abstract:
We present label-free functional photoacoustic imaging of the ocular microvasculature in living animals. The anterior segment of an adult mouse was imaged with a laser exposure level well within the American National Standards Institute safety standards. Individual red blood cells traveling along the iris capillaries were clearly resolved, and the hemoglobin oxygen saturation in the iris microvasculature was imaged spectrally. We believe that photoacoustic imaging has the potential to advance the diagnosis and treatment of ocular diseases in humans.
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