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Updated: Jun 10, 2026

Label-free Isolation and Enrichment of Cells Through Contactless Dielectrophoresis
Published on: September 3, 2013
A unified approach to dielectric single cell analysis: impedance and dielectrophoretic force spectroscopy
Ana Valero1, Thomas Braschler, Philippe Renaud
1Microsystems Laboratory, Ecole Polytechnique Federale de Lausanne, EPFL, BM 3.124 Station 17, Lausanne, Switzerland. ana.valero@epfl.ch
Abstract:
In this review we present a unified approach for single cell dielectric spectroscopy. Impedance spectroscopy and dielectrophoretic cell sorting, current microtechnologies applied in electrical analysis of single cells are discussed based on their closely related physical principles. In addition, examples of microfluidic devices will be presented: a microfabricated flow cytometer for single cell discrimination based on impedance analysis and a miniaturized continuous dielectrophoretic cell sorter, both using the concept of liquid electrodes. Using the experimental results obtained from both microdevices, we give a comparative overview over the dielectrophoretic sorting and impedance spectroscopy.
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