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Neurosurgical advances in cancer pain management
Ahmed M Raslan1, Kim J Burchiel
1Department of Neurological Surgery, Oregon Health & Science University, 3303 Southwest Bond Avenue, Portland, OR 97239, USA.
Abstract:
Neurosurgical procedures to treat pain are mainly destructive and involve the spinal cord and occasionally the brain. Targets include the spinothalamic tract, the trigeminal tract nucleus, the midline ascending visceral pain pathway, the brainstem spinal lemniscus, the thalamus, and the cingulate gyrus. Since the introduction of intrathecal opioids, the need for neurosurgical destructive procedures has been in decline. In recent years, cordotomy, trigeminal tractotomy, and dorsal root entry zone (DREZ) operations are the neurosurgical procedures most often utilized to treat cancer pain. The addition of CT guidance to spinal cord pain pathway ablation was a major addition and refinement to the procedure. Here the authors review the latest techniques and recently published results for CT-guided cordotomy, CT-guided trigeminal tractotomy, and DREZ operations utilized to treat cancer pain.
Insights
Neurosurgical pain treatments, including cordotomy and DREZ operations, are increasingly refined with CT guidance. These advanced techniques offer improved options for managing cancer pain, reducing reliance on destructive procedures.
Area of Science:
- Neurosurgery
- Pain Management
- Oncology
Background:
- Neurosurgical pain treatments are often destructive, targeting specific neural pathways in the spinal cord or brain.
- The advent of intrathecal opioids has decreased the need for ablative neurosurgical procedures.
- Current neurosurgical interventions for cancer pain primarily include cordotomy, trigeminal tractotomy, and dorsal root entry zone (DREZ) operations.
Purpose of the Study:
- To review the latest techniques and outcomes for CT-guided neurosurgical pain procedures.
- To highlight advancements in CT-guided cordotomy, trigeminal tractotomy, and DREZ operations for cancer pain management.
Main Methods:
- Review of recent literature on CT-guided cordotomy, trigeminal tractotomy, and DREZ operations.
- Focus on techniques and published results for these specific neurosurgical interventions.
- Inclusion of CT guidance as a key refinement in spinal cord pain pathway ablation.
Main Results:
- CT guidance has significantly refined spinal cord pain pathway ablation techniques.
- Cordotomy, trigeminal tractotomy, and DREZ operations remain key neurosurgical options for cancer pain.
- The review synthesizes the latest advancements and outcomes for these CT-guided procedures.
Conclusions:
- CT-guided neurosurgical procedures represent an advancement in treating cancer pain.
- These techniques offer refined options for pain management, particularly for intractable cancer pain.
- Continued research and application of CT guidance are crucial for optimizing neurosurgical pain interventions.
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