Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Cardiomyopathy IV: Restrictive Cardiomyopathy01:29

Cardiomyopathy IV: Restrictive Cardiomyopathy

Restrictive cardiomyopathy (RCM) is a rare heart muscle disease characterized by impaired ventricular filling due to stiffened ventricular walls, leading to significant diastolic dysfunction.EtiologyRestrictive cardiomyopathy can arise from both inherited and acquired diseases, many of which are systemic. It is categorized into four main types: infiltrative, storage, non-infiltrative, and endomyocardial diseases.Infiltrative diseases, such as amyloidosis, lead to RCM by depositing amyloid...
Cardiomyopathy I: Introduction and Classification01:25

Cardiomyopathy I: Introduction and Classification

Cardiomyopathy, or CMP, is a group of diseases affecting the myocardial structure, impairing its ability to pump blood effectively. This condition can lead to arrhythmias, heart failure, or sudden cardiac death.Cardiomyopathies are classified into primary and secondary categories:Primary Cardiomyopathy refers to conditions involving only the heart muscle that are often idiopathic (of unknown cause) or genetic. They primarily affect the myocardium without the involvement of other systemic...
Cardiomyopathy III: Hypertrophic Cardiomyopathy01:29

Cardiomyopathy III: Hypertrophic Cardiomyopathy

Hypertrophic cardiomyopathy, or HCM, is an autosomal dominant genetic disorder characterized by asymmetric left ventricular hypertrophy without ventricular dilation. It is more common in men and is typically diagnosed in young, athletic adults.EtiologyHCM is primarily genetic and is caused by mutations in genes encoding sarcomeric proteins. Researchers have identified over 1400 mutations across at least 11 different genes. Among these, the most frequently occurring mutations are found in the...
Cardiomyopathy II: Dilated Cardiomyopathy01:30

Cardiomyopathy II: Dilated Cardiomyopathy

Dilated cardiomyopathy, or DCM, is a progressive myocardial disorder characterized by ventricular chamber dilation and contractile dysfunction.EtiologyVarious factors can cause DCM, including hypertension and heavy alcohol intake, which contribute to the weakening and enlargement of the heart muscle. Viral infections, such as Coxsackievirus B, adenoviruses, and influenza, can lead to DCM by causing inflammation and damage to heart tissue. Certain chemotherapeutic agents, including daunorubicin,...
Rheumatic Heart Disease I: Introduction01:23

Rheumatic Heart Disease I: Introduction

Rheumatic heart disease or RHD is a chronic condition that results from rheumatic fever, causing permanent damage to the heart valves.Etiology and Risk FactorsIt primarily arises from rheumatic fever, an inflammatory disease that can develop after untreated or inadequately treated group A streptococcal (GAS) pharyngitis. Streptococcus spreads through direct contact with oral or respiratory secretions. While the bacteria are the causative agents, factors like malnutrition, overcrowding, poor...
Cardiomyopathy V: Interprofessional Care01:29

Cardiomyopathy V: Interprofessional Care

Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Occupational category, job type, and sarcoidosis: Findings from a French multicenter study.

Pulmonology·2026
Same author

Immunological efficacy and safety of influenza vaccination in adults with sarcoidosis: the SARCOVAC study.

Vaccine·2026
Same author

Pulmonary sarcoïdosis presenting as acute hypoxemic respiratory failure.

Respiratory medicine and research·2026
Same author

Considering molecular pharmacology for sarcoidosis treatment.

The Lancet. Respiratory medicine·2026
Same author

Incidence of New Comorbidities After Steroid Use in Patients With Sarcoidosis: An International Cross-Sectional Survey.

Chest·2025
Same author

Circulating Endothelial Compartment and Progenitor Cell Dynamics in Idiopathic Pulmonary Fibrosis: Findings from the COFI Trial.

Stem cell reviews and reports·2025

Related Experiment Videos

Cardiac sarcoidosis.

Hilario Nunes1, Olivia Freynet, Nicolas Naggara

  • 1Service de Pneumologie, Hôpital Avicenne, Assistance Publique - Hôpitaux de Paris, Bobigny, France. hilario.nunes@avc.aphp.fr

Seminars in Respiratory and Critical Care Medicine
|July 29, 2010
PubMed
Summary

Cardiac sarcoidosis (CS) presents diagnostic challenges, often manifesting as conduction abnormalities or arrhythmias. Early detection through medical history, ECG, and advanced imaging is crucial for managing this serious heart condition.

Related Experiment Videos

Area of Science:

  • Cardiology
  • Immunology
  • Pulmonology

Background:

  • Cardiac sarcoidosis (CS) is a significant complication of sarcoidosis, affecting 20-30% of patients, though clinical presentation is less common.
  • CS can involve the myocardium, pericardium, and endocardium, leading to diverse cardiac issues.

Purpose of the Study:

  • To review the clinical manifestations, diagnostic approaches, and treatment strategies for cardiac sarcoidosis.
  • To highlight the challenges in diagnosing CS and the evolving role of imaging modalities.

Main Methods:

  • Review of medical literature on cardiac sarcoidosis.
  • Discussion of diagnostic tools including ECG, echocardiography, scintigraphy, PET, and cardiac magnetic resonance (CMR).
  • Analysis of prognostic indicators and current treatment paradigms.

Main Results:

  • CS commonly causes conduction defects, ventricular arrhythmias, heart failure, and sudden death.
  • Diagnosis lacks a gold standard; endomyocardial biopsy has low sensitivity.
  • CMR offers radiation-free imaging but is limited by cardiac devices.

Conclusions:

  • Early detection and management of CS are vital, requiring a multidisciplinary approach.
  • Systemic corticosteroids, antiarrhythmic agents, and device implantation are key treatments.
  • Further research is needed to define the optimal role of novel imaging techniques in CS diagnosis.