Related Experiment Video
Updated: Jun 10, 2026

Generation of Hypoparathyroid Rats via Carbon-Nanoparticle-Assisted Parathyroidectomy
Published on: July 14, 2023
[Parathyroid hormone injection to counteract delayed bone fractures]
C E Brunnemann1, E C Reisinger, D Ganzer
1Klinik für Innere Medizin II, Universitätsklinikum Rostock.
Case History And Clinical Findings:
Two women, aged 71 and 53 years with periprosthetic fractures of the left femur and an 18 year old man with a non-union of fracture of the left radius presented for assessment and treatment.
Investigations:
Serial radiographs showed that osteosynthesis and/or autogenous bone-grafting and multiple revisions had not resulted in healing of the fractures.
Treatment And Clinical Course:
In all three patients parathyroid hormone (teriparatide), 20 to 60 microg, was injected subcutaneously once daily for 6 - 10 weeks. Subsequently a stable consolidation of the bone occurred in all of them.
Conclusion:
Administration of parathyroid hormone can induce stable consolidation of the bone in non-unions and delayed healing of bone fractures.
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