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Updated: Jun 10, 2026

Neonatal Murine Cochlear Explant Technique as an In Vitro Screening Tool in Hearing Research
Published on: June 8, 2017
Newborn hearing screening: a regional example for national care
O A Adelola1, V Papanikolaou, P Gormley
1Department of Otolaryngology, Head & Neck Surgery, Galway University Hospitals, Galway. adelolab@hotmail.com
Early hearing screening for congenital permanent childhood hearing impairment (PCHI) using a two-stage UNHS program is effective. This approach accurately identifies PCHI in newborns, supporting timely intervention and development.
Area of Science:
- Audiology
- Pediatrics
- Public Health
Background:
- Congenital Permanent Childhood Hearing Impairment (PCHI) negatively impacts language, cognition, and social integration.
- Early detection through Universal Newborn Hearing Screening (UNHS) is crucial for mitigating these effects.
Purpose of the Study:
- To describe the experience and results of a UNHS program implemented in the West of Ireland since 2000.
- To evaluate the accuracy, feasibility, and effectiveness of a two-stage UNHS protocol.
Main Methods:
- A two-stage screening protocol was used for neonates born between October 2000 and November 2007.
- Stage 1: Transient Evoked Oto-Acoustic Emissions (TEOAEs) for all neonates.
- Stage 2: Automated Auditory Brainstem Response (AABR) for non-pass TEOAE and audiological risk neonates.
Main Results:
- Screening coverage reached 98% (25,742/26,281 neonates).
- The prevalence of PCHI was 1.21 per 1000 live births (31 cases identified).
- The two-stage protocol demonstrated high accuracy and feasibility.
Conclusions:
- A hospital-based, two-stage UNHS protocol utilizing TEOAEs and AABR is accurate, feasible, and effective for identifying PCHI.
- This screening program facilitates early detection and intervention for hearing impairment in newborns.
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