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Ulcerative cutaneous polyarteritis nodosa treated with mycophenolate mofetil and pentoxifylline
Nicolas Kluger1, Bernard Guillot, Didier Bessis
1Université Montpellier I, Service de Dermatologie, Hôpital Saint-Eloi, CHU de Montpellier, Montpellier, France. icolaskluger@yahoo.fr
Abstract:
Cutaneous polyarteritis nodosa (CPAN) is a self-limited cutaneous vasculitis characterized by painful nodules, affecting mostly the lower limbs, and livedo reticularis. Despite its benign course, CPAN may display a chronic relapsing evolution with repeated exacerbations. Ulcerative CPAN has a more prolonged evolution and is associated with peripheral neuropathy. We report on a patient with a 20-year history of ulcerative and painful CPAN, refractory to multiple immunosuppressive treatments, treated successfully by mycophenolate mofetil and pentoxifylline.
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