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Related Concept Videos

Poliomyelitis01:17

Poliomyelitis

Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
Chickenpox01:20

Chickenpox

Chickenpox is an acute, highly contagious disease caused by the varicella-zoster virus (VZV), a double-stranded DNA virus belonging to the Herpesviridae family. Its transmission occurs primarily through the inhalation of respiratory droplets or direct contact with vesicular fluid from skin lesions. The incubation period typically ranges from 10 to 21 days, during which the virus replicates and disseminates through sequential phases within the host. Although generally self-limiting in children,...
Pneumonia I: Introduction01:30

Pneumonia I: Introduction

Pneumonia is an acute respiratory infection that targets the lungs, specifically the alveoli. These tiny air sacs, essential for oxygen exchange, become engorged with pus and fluid, severely hindering breathing, decreasing oxygen absorption, and causing significant pain and discomfort during respiration.
Risk Factors
Various factors influence the likelihood of developing pneumonia. Age plays a crucial role, with infants, children under two, and individuals over 65 at increased risk due to their...
Pneumonia I: Introduction01:29

Pneumonia I: Introduction

Pneumonia is an infection of the lower respiratory tract that leads to inflammation of the lung parenchyma, often resulting in the accumulation of inflammatory exudate in the alveoli and airways. Unlike the watery, low-protein fluid exudate in pulmonary edema, the exudate in this case is a thick fluid rich in immune cells, proteins, and debris produced during infection and inflammation.This impairs gas exchange and can lead to consolidation of lung tissue. The infection may be caused by a...
Atypical Pneumonia01:14

Atypical Pneumonia

Atypical pneumonia, often caused by Mycoplasma pneumoniae, is a form of pulmonary infection that differs from the classical presentation of bacterial pneumonia in both its cause and clinical symptoms. Mycoplasma pneumoniae is a pleomorphic bacterium notable for its lack of a rigid cell wall. This structural characteristic imparts resistance to beta-lactam antibiotics and significantly influences the bacterium’s behavior within the human host.Other pathogens responsible for the disease include...
Acute Pharyngitis01:30

Acute Pharyngitis

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Acute pharyngitis is the inflammation of the back of the throat (pharynx), commonly resulting in a sore throat. It is a frequently encountered condition that prompts individuals to seek medical advice.
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Acute pharyngitis can be categorized based on its underlying cause:

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Related Experiment Video

Updated: Jun 10, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Panniculitis in childhood.

Ingrid C Polcari1, Sarah L Stein

  • 1Section of Dermatology, University of Chicago Medical Center, Chicago, Illinois, USA. ingrid.polcari@uchospitals.edu

Dermatologic Therapy
|July 30, 2010
PubMed
Summary
This summary is machine-generated.

Panniculitis is subcutaneous fat inflammation, often presenting as tender nodules. Pediatric cases include specific types, and diagnosis may require pathology, with treatment varying by cause.

Related Experiment Videos

Last Updated: Jun 10, 2026

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
08:50

A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development

Published on: June 24, 2020

Area of Science:

  • Dermatology
  • Pediatrics
  • Pathology

Background:

  • Panniculitis involves inflammation of the subcutaneous fat.
  • It can be a primary condition or secondary to systemic diseases.
  • Certain forms are prevalent in children, including erythema nodosum and neonatal panniculitides.

Purpose of the Study:

  • To review the spectrum of panniculitis, focusing on pediatric presentations.
  • To highlight diagnostic clues and the role of pathology.
  • To outline general and specific treatment approaches.

Main Methods:

  • Literature review of panniculitis, with emphasis on pediatric cases.
  • Analysis of clinical presentations and diagnostic modalities.
  • Summary of treatment strategies based on etiology.

Main Results:

  • The hallmark clinical sign is tender, erythematous subcutaneous nodules.
  • Diagnosis often necessitates histopathological examination.
  • Pediatric panniculitides have distinct entities like cold panniculitis and neonatal fat necrosis.

Conclusions:

  • Panniculitis diagnosis relies on clinical suspicion and often requires pathology.
  • Management typically involves supportive care and addressing underlying conditions.
  • Specific therapies are crucial for infectious or malignancy-associated panniculitis.