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A Murine Model of Fetal Exposure to Maternal Inflammation to Study the Effects of Acute Chorioamnionitis on Newborn Intestinal Development
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Published on: June 24, 2020

Panniculitis in childhood

Ingrid C Polcari1, Sarah L Stein

  • 1Section of Dermatology, University of Chicago Medical Center, Chicago, Illinois, USA. ingrid.polcari@uchospitals.edu

Dermatologic Therapy
|July 30, 2010
PubMed

Insights

Panniculitis is subcutaneous fat inflammation, often presenting as tender nodules. Pediatric cases include specific types, and diagnosis may require pathology, with treatment varying by cause.

Area of Science:

  • Dermatology
  • Pediatrics
  • Pathology

Background:

  • Panniculitis involves inflammation of the subcutaneous fat.
  • It can be a primary condition or secondary to systemic diseases.
  • Certain forms are prevalent in children, including erythema nodosum and neonatal panniculitides.

Purpose of the Study:

  • To review the spectrum of panniculitis, focusing on pediatric presentations.
  • To highlight diagnostic clues and the role of pathology.
  • To outline general and specific treatment approaches.

Main Methods:

  • Literature review of panniculitis, with emphasis on pediatric cases.
  • Analysis of clinical presentations and diagnostic modalities.
  • Summary of treatment strategies based on etiology.

Main Results:

  • The hallmark clinical sign is tender, erythematous subcutaneous nodules.
  • Diagnosis often necessitates histopathological examination.
  • Pediatric panniculitides have distinct entities like cold panniculitis and neonatal fat necrosis.

Conclusions:

  • Panniculitis diagnosis relies on clinical suspicion and often requires pathology.
  • Management typically involves supportive care and addressing underlying conditions.
  • Specific therapies are crucial for infectious or malignancy-associated panniculitis.

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