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Related Experiment Video

Updated: Jun 10, 2026

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

A Computer-Based Platform for Aiding Clinicians in Eating Disorder Analysis and Diagnosis

Published on: May 10, 2022

Characterizing eating disorders in a personality disorders sample.

Eunice Yu Chen¹, Michael Sean McCloskey, Sara Michelson

¹Department of Psychiatry and Behavioral Neurosciences, The University of Chicago, Chicago, IL, USA. chen@bsd.uchicago.edu

Psychiatry Research

|July 30, 2010

Summary

Comorbid eating disorders (EDs) with personality disorders (PDs) increase risks for other mental health conditions and poorer functioning. This is especially true for females with EDs and PDs, who show more co-occurring disorders.

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Area of Science:

Psychiatry
Clinical Psychology
Mental Health Research

Background:

Comorbid eating disorders (EDs) and personality disorders (PDs) are linked to worse outcomes than either condition alone.
This comorbidity pattern extends to non-ED Axis I disorders and PDs, suggesting complex diagnostic interactions.

Purpose of the Study:

To investigate if EDs, compared to other non-ED Axis I disorders, confer greater risks within a PD sample.
To assess risks for additional non-ED Axis I and Axis II disorders, suicide attempts, self-injury, and psychosocial functioning.

Main Methods:

Standardized interviews were conducted with 166 females and 166 males diagnosed with PDs.
Data analysis focused on comparing individuals with EDs to those with other Axis I disorders within the PD sample.

Main Results:

In females with PDs, EDs were associated with a higher number of non-ED Axis I and Axis II disorders (especially borderline and avoidant PD) and poorer global functioning.
EDs in females with PDs were not significantly linked to increased suicide attempts or non-suicidal self-injury.
In males with PDs, EDs were linked to more Axis II disorders, particularly borderline PD, though this group was small and requires replication.

Conclusions:

EDs comorbid with PDs, especially in females, are associated with significant co-occurring psychopathology, including borderline and avoidant PD.
These findings suggest that targeting EDs in individuals with PDs may be crucial for comprehensive treatment, particularly for borderline PD in both sexes and avoidant PD in females.