Effects of diet on swine glyceride lipid metabolism

Swine were fed equal amounts of isoenergetic-isonitrogenous diets with low-fat or high-fat content. The high-fat diet, as well as starvation, suppressed the synthesis of fatty acid from glucose in adipose tissue. Diet had no effect on adipose tissue enzymes associated with glyceride synthesis; whereas starvation caused all activities expressed per g tissue to decrease. The hepatic enzyme activities associated with glyceride synthesis tended to be greater in swine fed the the high-fat diet compared to the low-fat diet. Starvation lowered the hepatic esterification of glycerol-3-phosphate but did not influence other enzymes.