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Updated: Jun 10, 2026

A Protocol for Measuring Cue Reactivity in a Rat Model of Cocaine Use Disorder
Published on: June 18, 2018
Prize-based contingency management is efficacious in cocaine-abusing patients with and without recent gambling
Nancy M Petry1, Sheila M Alessi
1Calhoun Cardiology Center, Department of Medicine, University of Connecticut Health Center MC-3944, 263 Farmington Avenue, Farmington, CT 06030-3944, USA. npetry@uchc.edu
Abstract:
Prize-based contingency management (CM) is efficacious in treating cocaine abuse, and the chance-based procedures of prize CM may be appealing to those who gamble. Using data from three randomized trials, we evaluated whether cocaine-abusing patients who had wagered in the month before treatment (n = 62) responded more favorably to prize CM than those who had not (n = 278). Participants were randomized to standard care (SC) or SC plus prize CM. Although prize CM was related to better outcomes overall, recent gambling was not associated with outcomes across or within treatment conditions. Gambling participation before treatment entry was associated with reductions in gambling over time, and this effect was more pronounced among those assigned to CM. These data suggest that prize CM is equally efficacious for substance-abusing patients who do and do not gamble, and they extend prior studies indicating that prize CM does not increase gambling.
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