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Perinatal mental distress and infant morbidity in Ethiopia: a cohort study
Joanna Ross1, Charlotte Hanlon, Girmay Medhin
1Faculty of Medicine, Department of Psychiatry, Addis Ababa University, Addis Ababa, Ethiopia.
Insights
Persistent perinatal common mental disorders (CMD) significantly increase infant diarrhea risk in Ethiopia. This association remained even when accounting for maternal health behaviors, highlighting a critical public health concern.
Area of Science:
- Global Health
- Perinatal Mental Health
- Child Health
Background:
- Common mental disorders (CMD) during pregnancy and postpartum periods are prevalent globally.
- Infant health outcomes are influenced by various factors, including maternal mental well-being and health behaviors.
- Ethiopia faces significant challenges in maternal and child health, necessitating research into risk factors for early infancy illnesses.
Purpose of the Study:
- To investigate the impact of perinatal common mental disorders (CMD) in Ethiopia on the risk of infant diarrhea, fever, and acute respiratory illnesses (ARI).
- To explore the potential mediating role of maternal health behaviors in the relationship between perinatal CMD and infant illnesses.
Main Methods:
- A population-based cohort study was conducted in a rural demographic surveillance site in Ethiopia.
- 1065 pregnant women were recruited, and 954 mother-infant pairs were followed up for the first two months of infancy.
- Perinatal CMD symptoms were assessed using the Self-Reporting Questionnaire (SRQ-20), with 'persistent' CMD defined as symptoms at both third trimester and 2 months postpartum.
Main Results:
- 26.0% of infants experienced diarrhea, 25.0% had ARI, and 35.1% had fever.
- Persistent perinatal CMD was associated with a 2.15 times increased risk of infant diarrhea (95% CI 1.39 to 3.34), independent of potential mediators like breastfeeding and hygiene.
- No significant association was found between persistent perinatal CMD and infant ARI or fever after adjusting for confounders.
Conclusions:
- Persistent perinatal common mental disorders are significantly associated with an increased risk of infant diarrhea in a low-income Ethiopian setting.
- Maternal health-promoting practices did not mediate the observed relationship between perinatal CMD and infant diarrhea.
- Further research is needed to elucidate the mechanisms underlying this association to inform effective intervention strategies for improving infant health.
Objectives:
(1) To investigate the impact of perinatal common mental disorders (CMD) in Ethiopia on the risk of key illnesses of early infancy: diarrhoea, fever and acute respiratory illnesses (ARI) and (2) to explore the potential mediating role of maternal health behaviours.
Design:
Population-based cohort study.
Setting:
Demographic surveillance site in a predominantly rural area of Ethiopia.
Participants:
1065 women (86.3% of eligible) in the third trimester of pregnancy were recruited and 954 (98.6%) of surviving, singleton mother-infant pairs were followed up until 2 months after birth.
Main Exposure Measure:
High levels of CMD symptoms, as measured by the locally validated Self-Reporting Questionnaire (SRQ-20 ≥6), in pregnancy only, postnatally only and at both time-points ('persistent').
Main Outcome Measures:
Maternal report of infant illness episodes in first 2 months of life.
Results:
The percentages of infants reported to have experienced diarrhoea, ARI and fever were 26.0%, 25.0% and 35.1%, respectively. Persistent perinatal CMD symptoms were associated with 2.15 times (95% CI 1.39 to 3.34) increased risk of infant diarrhoea in a fully adjusted model. The strength of association was not affected by including potential mediators: breast feeding practices, hygiene, the infant's vaccination status or impaired maternal functioning. Persistent perinatal CMD was not associated with infant ARI or fever after adjusting for confounders.
Conclusions:
Persistent perinatal CMD was associated with infant diarrhoea in this low-income country setting. The observed relationship was independent of maternal health-promoting practices. Future research should further explore the mechanisms underlying the observed association to inform intervention strategies.
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