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Whole-cell MALDI-TOF Mass Spectrometry is an Accurate and Rapid Method to Analyze Different Modes of Macrophage Activation
Published on: December 26, 2013
Scrub typhus associated macrophage activation syndrome
Gopinath Kango Gopal1, Chrispal Anugrah, Harikishan Boorugu
1Department of Medicine - 3, Christian Medical College, Vellore, India. gops95@yahoo.com
Tropical Doctor
|July 30, 2010
Summary
Macrophage activation syndrome (MAS) is rarely seen with scrub typhus. This report details three Indian cases of scrub typhus presenting with MAS, emphasizing early diagnosis and treatment for better outcomes.
Area of Science:
- Infectious Diseases
- Rheumatology
- Critical Care Medicine
Background:
- Macrophage activation syndrome (MAS) is a severe, life-threatening hyperinflammation.
- MAS can be primary or secondary to infections, autoimmune diseases, and malignancies.
- Scrub typhus, a bacterial infection, is an uncommon cause of MAS, with no prior reported cases from India.
