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Updated: Jun 10, 2026

Evaluation of Protein–Protein Interactions using an On-Membrane Digestion Technique
Published on: July 19, 2019
Yasutomi Nishizuka: father of protein kinase C
Shun-Ichi Nakamura1, Hirohei Yamamura
1Division of Biochemistry, Kobe University Graduate School of Medicine, Kobe 650-0017, Japan.
Abstract:
It is 6 years since we received the tragic news that our great mentor Dr Yasutomi Nishizuka passed away suddenly at the age of 72 years. Dr Nishizuka made several epoch-making discoveries in his life, e.g. the tryptophan metabolism, protein synthesis, ADP-ribosylation, regulation of cAMP-dependent protein kinase and discovery of protein kinase C (PKC). Among them his name will be remembered for a long time as a father of PKC, momentous discoveries in the twentieth century, which are still actively pursued by many laboratories worldwide.
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