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Herniated Intervertebral Disc l: Introduction

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Intervertebral disc herniation refers to the displacement of the nucleus pulposus (the gel-like inner core of the disc) through a tear or weakened area in the annulus fibrosus (the outer fibrous ring). The displaced disc material extends beyond the normal boundaries of the disc space and may compress or irritate nearby spinal nerve roots or, less commonly, the spinal cord.Etiology and Risk FactorsHerniation commonly results from degeneration, in which aging reduces disc hydration and...

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Updated: Jun 10, 2026

Transtubular Endoscopic Posterolateral Decompression for L5-S1 Lumbar Lateral Disc Herniation

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Published on: October 14, 2022

Migrated herniated disc mimicking a neoplasm.

Benjamin Hoch¹, George Hermann

¹Department of Pathology, University of Washington, Seattle, WA 98195, USA. bhoch@u.washington.edu

Skeletal Radiology

|July 30, 2010

Summary

This summary is machine-generated.

Migrated herniated discs can mimic tumors, posing diagnostic challenges. Recognizing their distinct radiological and pathological features is crucial to avoid misdiagnosis of cartilage neoplasms.

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Area of Science:

Neurosurgery
Pathology
Radiology

Background:

Disc sequestration involves herniated disc fragments migrating into the epidural space, fully detached from the parent disc.
Accurate diagnosis is essential, as these lesions can present with complex imaging and pathological characteristics.

Observation:

A case is presented where a migrated herniated disc was initially misdiagnosed as a cartilage neoplasm.
This misinterpretation was potentially influenced by radiological findings and the absence of herniated disc in the differential diagnosis.

Findings:

Magnetic Resonance (MR) imaging aids in differentiating migrated discs from other spinal lesions like abscesses, hematomas, or neoplasms.
Severe degenerative changes in herniated discs, including chondrocyte clustering and neovascularization, can lead to a pseudoneoplastic appearance pathologically.

Implications:

Enhanced awareness of migrated herniated disc features can prevent confusion with spinal tumors.
Correct radiological and pathological identification is key to appropriate patient management and treatment strategies.