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Updated: Jun 10, 2026

High-resolution Tandem Mass Spectrometry for Studying Chemical Constituents of Gynura bicolor DC
Published on: February 2, 2024
Coumarin derivatives from Gerbera saxatilis
Yin Qiang1, Yan-Jun Chen, Ya Li
1State Key Laboratory of Applied Organic Chemistry and College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou, Gansu, People's Republic of China.
Abstract:
Phytochemical investigation of Gerbera saxatilis (Astraceae) afforded three new coumarin derivatives 1- 3 and a known coumarin 4. Compounds 1 and 2 represent the first examples of the natural occurrence of the novel polycyclic pyrano[3-2c]coumarin carbon skeleton. The structures of compounds 1- 4 were characterized based on extensive spectroscopic analyses as well as comparison to the spectroscopic data reported. The structures of compounds 1 and 3 were further confirmed by X-ray data analyses. The cytotoxic activity of compounds 1- 4 was evaluated against selected cancer cell lines, including human leukemia cell (HL-60), human hepatoma cell (SMMC-7721), and human cervical carcinoma cell (HeLa) lines.
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