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Ovaries

Ovaries

The ovaries are roughly the size of almonds and measure approximately 2 to 3 centimeters in length. These paired structures are situated within the pelvic region and are anchored by the mesovarium—a peritoneal extension that also connects them to the wider structure of the broad ligament. The support system extends to the suspensory ligament, housing blood and lymphatic vessels. In addition, the ovarian ligament tethers the ovaries to the uterus.
On the ovarian surface, a layer of cuboidal...

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Related Experiment Video

Updated: Jun 10, 2026

In vitro Mesothelial Clearance Assay that Models the Early Steps of Ovarian Cancer Metastasis

In vitro Mesothelial Clearance Assay that Models the Early Steps of Ovarian Cancer Metastasis

Published on: February 17, 2012

[Node clearance in ovarian cancer].

Richard Villet¹, Delphine Salet-Lizee

¹Service de chirurgie viscérale et gynécologique, Groupe Hospitalier Diaconesses Croix Saint-Simon, 18, rue du Sergent Bauchat, 75012 Paris. rvillet@hopital-dcss.org

Bulletin De L'Academie Nationale De Medecine

|July 31, 2010

Summary

Iliac and lumboaortic lymphadenectomy in ovarian cancer may improve disease-free survival but not overall survival. Complete lymph node removal is crucial for therapeutic benefit in advanced stages.

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Last Updated: Jun 10, 2026

In vitro Mesothelial Clearance Assay that Models the Early Steps of Ovarian Cancer Metastasis

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Published on: February 17, 2012

Quantitation of Intra-peritoneal Ovarian Cancer Metastasis

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Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

Assessment of Ovarian Cancer Spheroid Attachment and Invasion of Mesothelial Cells in Real Time

Published on: May 20, 2014

Area of Science:

Gynecologic Oncology
Surgical Oncology
Immunology

Context:

Iliac and lumboaortic lymphadenectomy is a common surgical procedure for ovarian cancer.
The risks and immunological effects of these procedures are not fully understood.
Current imaging and palpation methods are less accurate than histological examination for detecting lymph node metastasis.

Purpose:

To evaluate the impact of lymphadenectomy on survival outcomes in ovarian cancer patients.
To determine the optimal extent and indications for lymphadenectomy in ovarian cancer treatment.
To clarify the diagnostic and therapeutic value of lymph node dissection.

Summary:

Two prospective randomized studies suggest lymphadenectomy improves disease-free survival but not overall survival in ovarian cancer, though findings are debated.
Complete lymphadenectomy, encompassing external iliac, primary iliac, and lumboaortic chains up to the left renal vein, is recommended for therapeutic value.
The necessity of lymphadenectomy depends on disease stage, grade, and histological type, being warranted in advanced stages with minimal residual disease.

Impact:

Findings contribute to refining surgical strategies for ovarian cancer management.
Highlights the importance of complete lymph node dissection for potential therapeutic gains.
Informs clinical decision-making regarding the extent and necessity of lymphadenectomy based on disease characteristics.