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Updated: Jun 10, 2026
06:43
Esophageal Heat Transfer for Patient Temperature Control and Targeted Temperature Management
Published on: November 21, 2017
Hot times in the intensive care unit
1Department of Medicine, University of Alabama at Birmingham School of Medicine, 420 Boshell Building, 1808 7th Avenue South, Birmingham, AL 35294, USA. eabraham@uab.edu
Critical Care (London, England)
|July 31, 2010
Summary
Intravenous ibuprofen may be a safe option for managing fever in intensive care unit patients who cannot take oral medications. Further research is needed to confirm its long-term safety and effectiveness.
Area of Science:
- Critical care medicine
- Pharmacology
Background:
- Fever is a frequent complication in intensive care units (ICUs).
- Limited pharmacologic options exist for fever management, especially for patients unable to tolerate enteral medications.
- Intravenous (IV) medications offer an alternative route for drug administration in critical care settings.
Discussion:
- A recent study suggests IV ibuprofen is safe and effective for critically ill patients.
- However, the study's small sample size and short 24-hour administration period limit definitive conclusions.
- The need for further investigation into IV ibuprofen's role in managing fever in ICUs is highlighted.
Key Insights:
- IV ibuprofen presents a potential therapeutic option for fever control in ICU patients.
- Current evidence is preliminary, necessitating cautious interpretation.
- The study underscores the importance of exploring alternative drug delivery methods for critically ill individuals.
Outlook:
- Additional clinical trials are required to establish the safety and efficacy of IV ibuprofen.
- Long-term outcomes and optimal dosing strategies for IV ibuprofen in critical care need to be determined.
- Further research could pave the way for broader clinical adoption of IV ibuprofen for fever management.
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