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Subcutaneous Infection of Methicillin Resistant Staphylococcus Aureus (MRSA)
Published on: February 9, 2011
Preoperative prevalence of methicillin-resistant Staphylococcus aureus (MRSA) colonization in patients undergoing
Brian D Nicholas1, Geeta Bhargave, Ayse Hatipoglu
1Department of Otolaryngology, Thomas Jefferson University Hospital, Philadelphia, PA 19107, USA. bnicholas44@gmail.com
Background:
The goal of this study was to determine the rates of carriage of methicillin-resistant Staphylococcus aureus among patients undergoing intranasal surgery.
Material/Methods:
One hundred and sixty five patients undergoing inpatient and outpatient rhinologic surgery over a six-month period were enrolled in the study. Patients completed a short questionnaire prior to surgery. Culture swabs of the anterior nares and nasal vestibule were sent to the microbiology lab for evaluation for methicillin-resistant Staphylococcus aureus. Cultures were grown on a MRSA-specific agar plate and were considered final after 48 hours of incubation. The primary endpoint was a positive MRSA culture.
Results:
Of the one hundred fifty seven patients with nasal cultures taken, two had positive cultures for methicillin-resistant Staphylococcus aureus. Of those with positive cultures, both had a history of prior infection with methicillin-resistant Staphylococcus aureus.
Conclusions:
While antibiotic usage among the study group is far higher than the national average, the rates of nasal carriage of methicillin-resistant Staphylococcus aureus mirrors that described in other studies for the general population. The authors conclude that methicillin-resistant Staphylococcus aureus does not represent a significant source of infection among those undergoing intranasal surgery.
Insights
Methicillin-resistant Staphylococcus aureus (MRSA) nasal carriage rates in patients undergoing intranasal surgery are similar to the general population. MRSA does not appear to be a significant infection source in these patients.
Area of Science:
- Otolaryngology
- Infectious Disease
- Microbiology
Background:
- Methicillin-resistant Staphylococcus aureus (MRSA) poses a significant healthcare challenge.
- Understanding MRSA carriage in patients undergoing surgery is crucial for infection control.
Purpose of the Study:
- To determine the prevalence of MRSA nasal carriage in patients scheduled for intranasal surgery.
- To assess the risk of MRSA infection in this surgical population.
Main Methods:
- Prospective study of 165 patients undergoing rhinologic surgery.
- Nasal cultures (anterior nares and vestibule) collected pre-operatively.
- MRSA identification using specific agar plates and 48-hour incubation.
Main Results:
- Two out of 157 patients (1.27%) had positive MRSA nasal cultures.
- Both positive cases had a prior history of MRSA infection.
- Nasal carriage rates were comparable to general population studies.
Conclusions:
- MRSA nasal carriage rates in patients undergoing intranasal surgery are low and similar to the general population.
- Despite high antibiotic usage in the study group, MRSA does not appear to be a significant source of surgical site infections.
- Routine MRSA screening may not be necessary for all patients undergoing intranasal procedures.
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Etiology
Possible causes of this condition include high blood pressure, trauma, low humidity, upper respiratory tract infections, allergies, foreign bodies, nasal inhalation of corticosteroids or illicit drugs, excessive use of decongestant nasal sprays, facial or nasal surgery, anatomic malformation, tumors, or systemic...
