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Updated: Jun 10, 2026

The Rodent Model of Nonarteritic Anterior Ischemic Optic Neuropathy (rNAION)
Published on: November 20, 2016
Nonarteritic anterior ischaemic optic neuropathy in Addison's disease
A H Ross1, S Haider, C C Bailey
1Bristol Eye Hospital, Bristol, UK.
Purpose:
To report three cases of Nonarteritic anterior ischaemic optic neuropathy (NAAION) in patients with Addison's disease.
Methods:
We present a retrospective review of patients presenting with NAAION with underlying Addison's disease.
Results:
Three eyes of two young patients presented with NAAION. Both patients had underlying Addison's disease with episodes of prolonged hypotension.
Conclusion:
To our knowledge, this is the first published report of NAAION associated with Addison's disease. As hypotension may be one of the few situations, in which NAAION may be treatable and the visual loss reversible, it is important to recognize and treat sustained episodes of hypotension in these individuals.
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