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Parry-Romberg Syndrome Associated with Localized Scleroderma
Jelena Maletic1, Vassiliki Tsirka, Panos Ioannides
1B Department of Neurology, AHEPA University Hospital, Thessaloniki, Greece.
Case Reports in Neurology
|July 31, 2010
Summary
Parry-Romberg syndrome, a rare neurocutaneous disorder, involves facial hemiatrophy and neurological issues like epilepsy. This case highlights its connection with localized scleroderma (morphea) and associated brain abnormalities.
Area of Science:
- Neurocutaneous disorders
- Dermatology
- Neurology
Background:
- Parry-Romberg syndrome is a rare, idiopathic neurocutaneous disorder.
- It features progressive hemifacial atrophy, often co-occurring with linear scleroderma 'en coup de sabre'.
- Neurological manifestations such as epilepsy, migraine, and facial pain are common, frequently linked to ipsilateral brain abnormalities.
Observation:
- A case of Parry-Romberg syndrome with neurological involvement is presented.
- The patient had a diagnosed history of localized scleroderma (morphea).
Findings:
- The case illustrates the overlap between Parry-Romberg syndrome, localized scleroderma, and neurological complications.
- It underscores the potential for ipsilateral brain abnormalities in patients with these conditions.
Implications:
- This case contributes to understanding the complex presentation of Parry-Romberg syndrome.
- It emphasizes the importance of thorough neurological and dermatological evaluation in affected individuals.
- Further research into the pathogenesis and management of this rare syndrome is warranted.
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