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Adsorption and bioactivity of tyrosine hydroxylase on gold surfaces and nanoparticles
Oyvind Halskau1, Sondre Volden, Ana C Calvo
1Department of Biomedicine, University of Bergen, Jonas Lies vei 91, N-5009 Bergen, Norway. Oyvind.Halskau@biomed.uib.no
Protein and Peptide Letters
|August 3, 2010
Abstract:
Tyrosine hydroxylase is studied in terms of adsorption behaviour on gold surfaces and various passivating layers. Results reveal differences in layer formation, where mercaptoundecanoic acid-coated gold shows the best potential in terms of adsorbed mass. Nanoparticles with this coating are subsequently tested for enzymatic activity, which remains at attenuated levels.
