Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Microbial Biosensors

Microbial Biosensors

Microbial biosensors are analytical devices that utilize living microbes to detect specific substances through measurable signals. These devices consist of two main components: biosensing organisms and signal-transducing elements. Biosensing organisms, such as Escherichia coli or Saccharomyces cerevisiae, are typically housed in multiwell plates connected to transducers, enabling rapid, real-time detection of target analytes.Signal Generation MechanismWhen a target analyte—such as...

Amperometry: Overview

Amperometry: Overview

Amperometry is a technique commonly used to measure the concentration of specific analytes in a solution by monitoring the electric current generated during an electrochemical reaction. It involves applying a constant potential between a working electrode and a reference electrode to measure the resulting current, which is proportional to the concentration of the analyte. The Clark oxygen electrode operates based on this principle of amperometry. It consists of a cathode and an anode enclosed...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

A Numerical Study on Molten Pool Behavior and Ribbon Thickness Under Varying Casting Parameters in Planar Flow Casting.

Materials (Basel, Switzerland)·2026

Same author

Oxidative stress-triggered UMPylation of SodA by YdiU modulates oxidative stress resistance in Salmonella.

Veterinary research·2026

Same author

DNA Nanobridge with Cascade Operation Logic on a Transistor for Comprehensive Evaluation of Respiratory Infection.

ACS applied materials & interfaces·2026

Same author

Association Between Stress Hyperglycemia Ratio and Death in Patients With Moderate to Severe Tricuspid Regurgitation.

Journal of the American Heart Association·2026

Same author

A pilot study assessing the feasibility of contrast-enhanced ultrasound for triaging fine-needle aspiration in lateral cervical lymph nodes of papillary thyroid carcinoma.

BMC cancer·2026

Same author

A rare case report: MRSA osteomyelitis after CRPP for pediatric distal both-bone forearm fracture.

BMC pediatrics·2026

Search research articles

Related Experiment Video

Updated: Jun 10, 2026

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose

Published on: December 30, 2025

An improved sensitivity nonenzymatic glucose biosensor based on a CuxO modified electrode.

Cuiling Li¹, Yi Su, Senwang Zhang

¹Changchun Institute of Applied Chemistry, Graduate School of Chinese Academy of Science, 5625 Renmin Street, Changchun 130022, PR China.

Biosensors & Bioelectronics

|August 3, 2010

Summary

This study presents an advanced enzymeless biosensor using a copper oxide (CuxO) on copper (Cu) electrode for efficient glucose detection. The novel CuxO/Cu biosensor demonstrates high sensitivity and a low detection limit, making it suitable for blood serum analysis.

More Related Videos

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Related Experiment Videos

Last Updated: Jun 10, 2026

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose

NiO Nanoflowers for Non-Enzymatic Amperometric Detection of Glucose

Published on: December 30, 2025

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Hollow Microneedle-based Sensor for Multiplexed Transdermal Electrochemical Sensing

Published on: June 1, 2012

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Dry Film Photoresist-based Electrochemical Microfluidic Biosensor Platform: Device Fabrication, On-chip Assay Preparation, and System Operation

Published on: September 19, 2017

Area of Science:

Electrochemistry
Materials Science
Biosensors

Background:

Development of sensitive and selective biosensors is crucial for disease diagnosis.
Enzymeless biosensors offer advantages in stability and cost-effectiveness over traditional enzyme-based sensors.
Copper oxides (CuxO) show promise as electrode materials due to their catalytic properties.

Purpose of the Study:

To investigate an enzymeless biosensor based on a CuxO/Cu electrode for glucose detection.
To characterize the CuxO nanostructured material and evaluate its electrochemical performance.
To assess the biosensor's applicability in real biological samples like blood serum.

Main Methods:

Fabrication of a CuxO/Cu electrode using nanostructured copper oxide.
X-ray Diffraction (XRD) for material composition analysis (Cu2O and CuO).
Field Emission Scanning Electron Microscopy (FESEM) for surface morphology.
Cyclic voltammetry to evaluate electrochemical performance for glucose detection.

Main Results:

XRD confirmed the presence of both Cu2O and CuO in the CuxO nanostructure.
FESEM revealed a flower-like morphology with a large surface area.
The CuxO/Cu electrode exhibited significantly higher peak currents compared to bare Cu foil and other CuxO modified electrodes.
The biosensor demonstrated excellent linearity (R=0.996), a low detection limit (0.049 mM), and high sensitivity (1.62 mA cm(-2) mM(-1)) for glucose.
Successful application in determining glucose levels in blood serum samples.

Conclusions:

The CuxO/Cu electrode is a highly effective material for developing advanced enzymeless glucose biosensors.
The unique nanostructure contributes to enhanced catalytic activity and sensing performance.
This CuxO/Cu based biosensor shows significant potential for practical applications in clinical diagnostics.