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Related Concept Videos

Hepatitis01:25

Hepatitis

Hepatitis is an inflammatory condition of the liver most commonly caused by hepatotropic viruses (A–E), though non-infectious causes such as alcohol and drugs also exist.Hepatitis AHepatitis A virus (HAV) is a non-enveloped RNA virus of the Picornaviridae family. It is primarily transmitted via the fecal-oral route, typically through ingestion of contaminated food or water. After ingestion, HAV enters the bloodstream through the oropharynx or intestinal epithelium and reaches the liver. The...
Viral Hepatitis I: Introduction01:28

Viral Hepatitis I: Introduction

Viral hepatitis is an inflammatory condition of the liver caused by infection with hepatotropic viruses, most commonly hepatitis A, B, C, D, and E. Despite variations in structure and transmission, all viruses mentioned infect hepatocytes and provoke immune responses that can hinder liver function. Additionally, some non-hepatotropic viruses can also lead to hepatic inflammation.Hepatitis A VirusHepatitis A virus (HAV) is transmitted through the fecal–oral route, typically by ingestion of food...
Blood Transfusion01:15

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test01:22

Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test

In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess the...

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Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
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Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA

Published on: December 15, 2023

[Post-transfusion hepatitis C. From screening to compensation].

O Ferrant1, A Bazin, A Girard

  • 1Unité de médecine légale, CHU Côte de Nacre, avenue de la Côte-de-Nâcre, 14033 Caen cedex 9, France. ophelie.ferrant@yahoo.fr

Transfusion Clinique Et Biologique : Journal De La Societe Francaise De Transfusion Sanguine
|August 3, 2010
PubMed
Summary
This summary is machine-generated.

Hepatitis C infections from blood transfusions in France were common before 1990. Enhanced safety measures have drastically reduced risks, but many infected individuals remain unaware of their status.

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A Protocol for Analyzing Hepatitis C Virus Replication
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Published on: June 26, 2014

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Last Updated: Jun 10, 2026

Real-Time Polymerase Chain Reaction-Based Detection and Quantification of Hepatitis B Virus DNA
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Published on: December 15, 2023

A Protocol for Analyzing Hepatitis C Virus Replication
13:04

A Protocol for Analyzing Hepatitis C Virus Replication

Published on: June 26, 2014

Area of Science:

  • Hepatology
  • Public Health
  • Transfusion Medicine

Background:

  • Hepatitis C virus (HCV) posed a significant risk to blood recipients in France before 1990, with estimates of 100,000-400,000 infections.
  • Advances in transfusion safety since 1990 have substantially lowered the risk of HCV transmission.
  • The long, often asymptomatic, incubation period of hepatitis C means many infected individuals remain undiagnosed.

Purpose of the Study:

  • To review the evolution of post-transfusion hepatitis C detection methods at Caen University Hospital.
  • To highlight the role of haemovigilance and blood product traceability in identifying at-risk individuals.
  • To discuss compensation avenues for victims of transfusion-transmitted hepatitis C.

Main Methods:

  • Review of historical data and institutional records regarding hepatitis C screening and detection campaigns.
  • Analysis of the impact of legislative changes and institutional policies on transfusion safety.
  • Examination of the function of haemovigilance systems and blood traceability in managing transfusion-related risks.

Main Results:

  • Implementation of various detection strategies over different periods, driven by regulatory and institutional initiatives.
  • Significant reduction in transfusion-associated hepatitis C transmission following improved safety protocols.
  • Ongoing challenge of identifying individuals with unknown hepatitis C serological status.

Conclusions:

  • Caen University Hospital has adapted its strategies for detecting post-transfusion hepatitis C in response to evolving scientific understanding and public health directives.
  • Haemovigilance and traceability are crucial components in managing transfusion safety and identifying past infections.
  • Addressing the long-term consequences for infected individuals, including compensation, remains an important consideration.