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Abstract:
This article has reviewed the diagnostic value of testicular biopsy in the evaluation of male infertility. In order to optimize the interpretation of morphologic findings, it is essential that a full medical and occupational history and careful hormonal evaluation be performed. A karyotype may be indicated in some cases. The pathologist has the opportunity to render a diagnostic opinion based on examination of seminiferous tubules and interstitium and correlated with the results of the history, physical examination, and laboratory studies. A rapid quantitative method is available for determining the likelihood that a significant epididymal obstruction exists that may be relieved surgically.