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Published on: December 22, 2023
[Arrhythmogenic cardiomyopathy with predominant left ventricular involvement]
Farid Aliyev1, Cengizhan Türkoğlu, Cengiz Celiker
1Istanbul Universitesi Kardiyoloji Enstitüsü Kardiyoloji Anabilim Dali, Istanbul, Turkey. drfaridaliyev@yahoo.com.tr
Summary
Arrhythmogenic cardiomyopathy can affect the left ventricle, mimicking other heart conditions. This review details left-dominant arrhythmogenic cardiomyopathy for better diagnosis and understanding.
Area of Science:
- Cardiology
- Genetics
- Pathology
Context:
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a known cause of sudden cardiac death.
- Left-dominant arrhythmogenic cardiomyopathy (LDAC) is an emerging clinical entity.
- LDAC may be misdiagnosed as idiopathic dilated cardiomyopathy.
Purpose:
- To review the current understanding of left-dominant arrhythmogenic cardiomyopathy.
- To differentiate LDAC from other cardiomyopathies.
- To highlight recent advancements in LDAC diagnosis and management.
Summary:
- Arrhythmogenic cardiomyopathy typically affects the right ventricle.
- A variant with predominant left ventricular involvement (LDAC) is increasingly recognized.
- LDAC presents diagnostic challenges due to overlapping features with other cardiomyopathies.
Impact:
- Improved diagnostic accuracy for left-dominant arrhythmogenic cardiomyopathy.
- Enhanced understanding of arrhythmogenic cardiomyopathy spectrum.
- Potential for earlier intervention and improved outcomes in affected patients.
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