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Medicine use from birth to age two years: the 2004 Pelotas (Brazil) Birth Cohort study
Edilson Almeida de Oliveira1, Andréa Dâmaso Bertoldi, Marlos Rodrigues Domingues
1Universidade do Vale do Rio dos Sinos, São Leopoldo, RS, Brasil.
Insights
Medicine use in young children remains high, with self-medication increasing as they age. This highlights the critical need for prioritizing rational medicine use in early childhood.
Area of Science:
- Pediatrics
- Pharmacology
- Public Health
Background:
- Childhood medicine use is a significant public health concern.
- Understanding patterns of medication use in early life is crucial for appropriate healthcare interventions.
Purpose of the Study:
- To describe medicine use patterns in children at three, 12, and 24 months of age.
- To analyze changes in medicine types, acquisition, and self-medication with age.
Main Methods:
- Cross-sectional study utilizing data from the 2004 Pelotas Birth Cohort in Southern Brazil.
- Home interviews with parents using standardized questionnaires to collect data on medicine use and related factors.
- Involved 3,985 children at three months, 3,907 at 12 months, and 3,868 at 24 months.
Main Results:
- Prevalence of medicine use was high: 65.0% at 3 months, 64.4% at 12 months, and 54.7% at 24 months.
- Self-medication increased with age, reaching 34% at 24 months, with a shift towards sporadic use.
- Therapeutic drug profiles changed significantly, with dermatological products common at 3 months, respiratory drugs at 12 months, and analgesics at 24 months.
Conclusions:
- High rates of medicine use in early childhood underscore the need for interventions promoting rational prescribing and use.
- The study emphasizes the importance of monitoring and guiding medicine consumption patterns from infancy.
Objective:
To describe medicine use by children at three, 12 and 24 months of age.
Methods:
Cross-sectional study using data from the 2004 Pelotas Birth Cohort (Southern Brazil), including: 3,985 children at three months, 3,907 children at 12 months, and 3,868 children at 24 months of age. The outcome investigated was use of medicine in the 15 days preceding the interview. Information on independent variables (medicine used, who indicated it, how it was obtained, periodicity of use, and therapeutic group) were collected using a standardized questionnaire administered during a home interview with the child's parents.
Results:
Prevalence of medicine use at three, 12, and 24 months was 65.0% (95% CI: 63.5;66.5), 64.4% (95% CI: 62.9;65.9), and 54.7% (95% CI: 53.1;56.2), respectively. As age increased, there was a reduction in the total number of medicines used and an increase in self-medicine, which reached 34% at 24 months. Furthermore, frequency of sporadic medicine use increased, while that of continuous use decreased. Medicine was purchased mainly using private resources, with roughly 10% of drugs being purchased through the Brazilian National Health Care System. The profile of medicine types used also changed with age. The type of medicine most frequently used were dermatological products (36%) at three months; respiratory system drugs (24%) at 12 months; and analgesics (26%) at 24 months of age. Compared to three months, medicine use at 24 months was characterized by decreased use of digestive tract and metabolism drugs, drugs for the sensory organs, cardiovascular system drugs, and dermatological products, and an increase in systemic anti-infectious drugs, medicine for the skeletomuscular and respiratory systems, analgesics, insecticides, and repellents.
Conclusions:
Medicine use in this cohort was high and indicates the need for prioritizing rational use of medicine in early life.
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