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Updated: Jun 10, 2026

Drug-Induced Sleep Endoscopy (DISE) with Target Controlled Infusion (TCI) and Bispectral Analysis in Obstructive Sleep Apnea
Published on: December 6, 2016
The changing faces of endoscopic sedation.
Brijen Shah1, Lawrence B Cohen
1Mount Sinai School of Medicine, NY, USA.
Sedation for digestive endoscopy is increasing globally, improving patient experience and exam quality. While moderate sedation is standard, propofol use is growing, despite ongoing debates about endoscopist administration.
Area of Science:
- Gastroenterology
- Anesthesiology
Background:
- Sedation practices for digestive endoscopy are evolving worldwide.
- There is a global trend towards increased sedation use in routine endoscopic procedures.
- Sedation enhances patient satisfaction, compliance with screening, and endoscopic examination quality.
Purpose of the Study:
- To discuss the evolving trends in sedation for digestive endoscopy.
- To highlight the increasing use of propofol and ongoing controversies.
- To explore future sedation techniques like fospropofol and computer-assisted sedation.
Main Methods:
- Review of current sedation practices in digestive endoscopy.
- Discussion of the increasing utilization of propofol.
- Analysis of controversies surrounding endoscopist-directed propofol administration.
- Exploration of emerging sedation technologies and future trends.
Main Results:
- Moderate sedation (benzodiazepine and opioid) remains the global standard.
- Propofol use is increasing in some countries, offering benefits but facing administration debates.
- Policy changes in the USA may impact endoscopist-directed propofol use.
- Future trends include fospropofol and computer-assisted personalized sedation.
Conclusions:
- Sedation is integral to modern digestive endoscopy, improving patient outcomes and procedure quality.
- The debate on propofol administration highlights the need for evidence-based guidelines.
- Emerging technologies promise further advancements in sedation safety and efficacy.
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