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Updated: Jun 10, 2026

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
Published on: April 11, 2018
Ethical considerations in choosing a model for population-based cystic fibrosis carrier screening
Lucy J Modra1, R John Massie, Martin B Delatycki
1Austin Health, Melbourne, VIC, Australia. lucy.modra@austin.org.au
Abstract:
Cystic fibrosis (CF) carrier testing can be used to inform reproductive decision making, allowing carriers to avoid having a child with CF. A government-funded, population-based CF carrier screening program would allow greater equity of access to this test. The setting in which CF carrier screening is offered significantly affects the extent to which participants make well informed, voluntary decisions to accept or decline testing. Screening offered before pregnancy and in non-clinical environments better promotes participant autonomy than screening offered in the prenatal consultation.
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