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Related Concept Videos

Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Peripheral Artery Disease III: Interprofessional Care01:27

Peripheral Artery Disease III: Interprofessional Care

Peripheral Artery Disease (PAD) is characterized by narrowed arteries that diminish blood flow to the extremities. Effective management of PAD requires an interprofessional approach involving various healthcare professionals. The critical aspects of interprofessional care for PAD patients focus on risk factor modification, drug therapy, exercise therapy, nutrition therapy, critical limb ischemia care, and interventional radiology and surgical procedures.The primary treatment goal for PAD...
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Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
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Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
Ischemic Stroke ll: Pathophysiology01:15

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An ischemic stroke occurs when a cerebral blood vessel becomes obstructed, most often by a thrombus or embolus, interrupting the delivery of oxygen and glucose to brain tissue. Because neurons rely on continuous aerobic metabolism, energy failure begins within minutes of reduced perfusion. The region receiving the least blood flow becomes the infarct core, an area of irreversible cellular death. Surrounding this core lies the penumbra, a zone of hypoperfused but still viable tissue that is...
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Related Experiment Video

Updated: Jun 10, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
09:21

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Published on: January 18, 2018

Direct PTA for Acute Ischemic Stroke.

J Uno1

  • 1Department of Neurosurgery, Baba Memorial Hospital; Sakai, Japan.

Interventional Neuroradiology : Journal of Peritherapeutic Neuroradiology, Surgical Procedures and Related Neurosciences
|August 4, 2010
PubMed
Summary

Direct percutaneous transluminal angioplasty (PTA) successfully recanalized 64% of occluded arteries in acute ischemic stroke patients. This promising technique showed no complications and offers a novel treatment option.

Area of Science:

  • Neurology
  • Interventional Radiology
  • Vascular Medicine

Background:

  • Acute ischemic stroke poses a significant health challenge.
  • Effective recanalization techniques are crucial for improving patient outcomes.
  • Existing treatments like intraarterial fibrinolytic therapy have limitations.

Purpose of the Study:

  • To evaluate the safety and efficacy of direct percutaneous transluminal angioplasty (PTA) for acute ischemic stroke.
  • To assess the recanalization rates in various cerebral arteries.
  • To compare the effectiveness of direct PTA with existing therapies.

Main Methods:

  • Direct PTA was performed on 23 patients diagnosed with acute ischemic stroke.
  • Arterial occlusions were identified in the internal carotid artery (ICA), vertebral artery (VA), middle cerebral artery (MCA), and basilar artery (BA).

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  • Recanalization was assessed post-procedure.
  • Main Results:

    • Direct PTA was performed on 23 patients with acute ischemic stroke.
    • Occlusions were identified in extracranial ICA (6), extracranial VA (1), intracranial ICA (3), MCA (12), and BA (1).
    • Recanalization was observed in 14 of 22 occluded arteries (64%), with rates comparable to intraarterial fibrinolytic therapy. No complications were reported.

    Conclusions:

    • Direct PTA is a safe and effective recanalization technique for acute ischemic stroke.
    • The procedure achieved a significant recanalization rate, comparable to established therapies.
    • Direct PTA represents a promising novel therapeutic option for stroke management.