Related Experiment Video
Updated: Jun 10, 2026

05:54
Real-Time Dynamic Navigation System for the Precise Quad-Zygomatic Implant Placement in a Patient with a Severely Atrophic Maxilla
Published on: October 18, 2021
Making bone II: maxillary sinus augmentation with mononuclear cells--case report with a new clinical method
Rainer Schmelzeisen1, Ralf Gutwald, Toshiyuki Oshima
1Department of Oral and Craniomaxillofacial Surgery, University Hospital Freiburg, Hugstetter Str. 55, D-79106 Freiburg, Germany.
The British Journal of Oral & Maxillofacial Surgery
|August 4, 2010
Summary
Simplified bone marrow aspirate concentrate (BMAC™) regeneration of hard tissue shows promise. BMAC™ with biomaterials can form sufficient bone for implants in 3 months, minimizing donor site issues.
Area of Science:
- Regenerative medicine
- Biomaterials science
- Orthopedic surgery
Background:
- Hard tissue regeneration is crucial for reconstructive surgery and dental implants.
- Current methods often involve invasive procedures with significant donor site morbidity.
- Bone marrow aspirate concentrate (BMAC™) offers a source of regenerative cells.
Observation:
- A simplified method utilizing bone marrow aspirate concentrate (BMAC™) was developed.
- BMAC™ was combined with a suitable biomaterial for hard tissue regeneration.
- The procedure aimed to minimize donor site morbidity.
Findings:
- The combination of BMAC™ and biomaterial successfully regenerated hard tissue.
- Sufficient bone formation occurred within a 3-month period.
- This bone regeneration was adequate for the subsequent insertion of implants.
Implications:
- This simplified BMAC™ technique offers a viable option for hard tissue regeneration.
- The method has the potential to reduce patient recovery time and complications.
- It paves the way for more efficient and less invasive orthopedic and dental implant procedures.