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Cerebrum: Anatomical Overview I

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The main and largest component of the human brain is the cerebrum. The cerebrum consists of two main parts: the cerebral cortex, an outer layer with wrinkles or folds known as gyri and shallow grooves called sulci, and a deeper region beneath it. The cerebrum divides into two distinct hemispheres and contains five different lobes: the frontal, parietal, temporal, occipital, and insula. The central sulcus separates the frontal and parietal lobes and two functionally important gyri — the...

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Frontal Disconnection for Treating Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy (MOGHE) in the Frontal Lobe

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Gliomatosis cerebri.

Rymante Gleizniene¹, Ugnius Bucinskas, Saulius Lukosevicius

¹Department of Radiology, Kaunas University of Medicine, Eiveniu 2, 50009 Kaunas, Lithuania.

Medicina (Kaunas, Lithuania)

|August 4, 2010

Summary

Gliomatosis cerebri, a rare infiltrating brain tumor, presents challenges in diagnosis due to its extensive spread. This case highlights imaging findings and pathological confirmation for this diffuse glial tumor.

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Area of Science:

Neuro-oncology
Neuroradiology
Pathology

Background:

Gliomatosis cerebri is a rare, diffusely infiltrating glial tumor affecting multiple brain lobes.
Tumor infiltrative extent often disproportionate to histological and clinical presentation.

Observation:

Computed tomography (CT) showed minimal midline shift and mild ventricular dilatation without significant density changes.
Magnetic resonance tomography (MRT) revealed progressive, multi-lobar hyperintense signals on T2W/SE and T2W/FLAIR images, with no T1W enhancement.

Findings:

Stereotactic biopsy confirmed diffuse glial tumor changes consistent with gliomatosis cerebri.
Radiological findings were initially subtle, necessitating advanced imaging and biopsy for definitive diagnosis.

Implications:

This case underscores the importance of comprehensive radiological assessment, including advanced MRI techniques, for diagnosing gliomatosis cerebri.
Discussion includes various imaging modalities like CT, MRI spectroscopy, and PET for evaluating this challenging brain tumor.