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Updated: Jun 10, 2026
07:36
Isolation of Human Lymphatic Endothelial Cells by Multi-parameter Fluorescence-activated Cell Sorting
Published on: May 1, 2015
Vascular anomalies and lymphedema
Harvey Chim1, Beth Drolet, Kelly Duffy
1Cleveland, Ohio; Milwaukee, Wis.; and Tokyo, Japan From the Department of Plastic Surgery, Case Western Reserve University; the Department of Dermatology, Children's Hospital of Wisconsin; and the Department of Plastic and Reconstructive Surgery, University of Tokyo.
Plastic and Reconstructive Surgery
|August 4, 2010
Summary
Vascular anomalies, including tumors and malformations, require understanding of their distinct natural histories and treatment. Lymphaticovenular anastomoses offer a new approach for lymphedema treatment.
Area of Science:
- Vascular anomalies encompass both tumors and malformations.
- The International Society for the Study of Vascular Anomalies classification is the standard for diagnosis and treatment.
Background:
- Vascular anomalies are common in the general population.
- Accurate classification guides diagnosis, evaluation, and treatment strategies.
Purpose of the Study:
- To differentiate vascular tumors from malformations.
- To outline the distinct natural histories of hemangiomas and vascular malformations.
- To detail the evaluation and treatment of various vascular anomalies and lymphedema.
Main Methods:
- Distinguishing clinical courses: hemangiomas involute, while malformations grow with the patient.
- Reviewing current treatment modalities for vascular tumors and malformations.
- Highlighting supermicrosurgical techniques for lymphaticovenular anastomoses in lymphedema.
Main Results:
- Hemangiomas have predictable stages (proliferation, involution); malformations grow and persist.
- Diverse treatments exist for vascular tumors and malformations.
- Lymphaticovenular anastomoses are effective for extremity lymphedema.
Conclusions:
- Plastic surgeons must understand vascular anomaly classification and treatment.
- Lymphedema management benefits from knowledge of lymphaticovenular anastomoses.
- Supermicrosurgery enables advanced lymphaticovenular anastomosis techniques.
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