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Evidence-based Knowledge Synthesis and Hypothesis Validation: Navigating Biomedical Knowledge Bases via Explainable AI and Agentic Systems
Published on: June 13, 2025
Developing good clinical questions and finding the best evidence to answer those questions
Patricia B Burns1, Kevin C Chung
1Ann Arbor, Mich. From the Section of Plastic Surgery, Department of Surgery, University of Michigan Health System.
Abstract:
Evidence-based medicine involves the integration of the best scientific evidence available with physician experience and patient preferences. One of the first steps in evidence-based medicine involves developing a question based on issues encountered with patients or a disease and finding evidence to answer the question. This article is a guide to plastic surgeons in how to begin the practice of evidence-based medicine by developing clinical questions and finding evidence to answer these questions.
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