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Updated: Jun 10, 2026

Transport Properties of Ibuprofen Encapsulated in Cyclodextrin Nanosponge Hydrogels: A Proton HR-MAS NMR Spectroscopy Study
Published on: August 15, 2016
Host-guest system of nimbin and beta-cyclodextrin or its derivatives: preparation, characterization, inclusion mode,
Li-Juan Yang1, Bo Yang, Wen Chen
1Key Laboratory of Medicinal Chemistry for Natural Resources, Ministry of Education, School of Chemical Science and Technology, Yunnan University, Kunming, 650091, People's Republic of China.
Abstract:
The inclusion complexation behavior, characterization, and binding ability of nimbin with beta-cyclodextrin (beta-CD) and its derivatives were investigated in both solution and the solid state by means of XRD, DSC, (1)H and 2D NMR, and UV-vis spectroscopy. The results showed that the water solubility and thermal stability of nimbin were obviously increased in the inclusion complex with cyclodextrins. This satisfactory water solubility and high thermal stability of the nimbin/CD complexes will be potentially useful for their application as herbal medicines or healthcare products.
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