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Related Concept Videos

Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

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Related Experiment Video

Updated: Jun 10, 2026

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices
02:14

Underwater Endoscopic Injection Sclerotherapy for Gastroesophageal Varices

Published on: August 1, 2025

Endoscopic therapy for gastric varices.

S K Sarin1, S R Mishra

  • 1Department of Gastroenterology, G B Pant Hospital, University of Delhi, Institute of Liver and Biliary Sciences, New Delhi, India. shivsarin@gmail.com

Clinics in Liver Disease
|August 5, 2010
PubMed
Summary

Bleeding from gastric varices (GVs) is severe but less frequent than esophageal varices (EVs). Endoscopic cyanoacrylate glue injection is the preferred treatment for active gastric variceal bleeding and preventing recurrence.

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Area of Science:

  • Gastroenterology
  • Hepatology
  • Endoscopic interventions

Background:

  • Gastric varices (GVs) bleeding is often more severe than esophageal varices (EVs) bleeding.
  • Despite advancements, optimal treatment for GV bleeding remains debated.
  • High blood flow in GVs leads to rapid, profuse bleeding.

Purpose of the Study:

  • To review current endoscopic treatment modalities for gastric variceal bleeding.
  • To discuss primary and secondary prophylaxis strategies for gastric variceal bleeding.

Main Methods:

  • Review of current endoscopic treatment modalities.
  • Focus on endoscopic injection of cyanoacrylate glue.
  • Discussion of prophylactic strategies.

Main Results:

  • Endoscopic treatment is the preferred approach for bleeding GVs.
  • Cyanoacrylate glue injection is the treatment of choice for active GV bleeding and rebleeding prevention.
  • Current literature supports various endoscopic techniques.

Conclusions:

  • Endoscopic cyanoacrylate glue injection is highly effective for active gastric variceal bleeding.
  • Further consensus on optimal treatment strategies and prophylaxis is needed.
  • Endoscopic interventions offer the best approach for managing GVs.