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Related Concept Videos

Coronavirus01:29

Coronavirus

Coronaviruses, including the severe acute respiratory syndrome coronavirus (SARS-CoV), are enveloped viruses characterized by their single-stranded, positive-sense RNA genome and helical nucleocapsid structure. The hallmark of these viruses is their club-shaped spike (S) glycoproteins that protrude from the viral envelope, facilitating attachment to host cells. Typically, coronaviruses infect the upper respiratory tract, often causing mild or asymptomatic disease. However, certain strains like...
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Rabies is a lethal zoonotic disease caused by a single-stranded, negative-sense RNA virus of the Lyssavirus genus, within the family Rhabdoviridae. Its primary mode of transmission to humans is through bites or saliva-contaminated scratches from infected mammals such as dogs, bats, raccoons, or foxes. Transmission can also occur if infectious saliva contacts abraded skin or intact mucous membranes, including the conjunctiva.Viral Entry and Early ReplicationOnce introduced at the bite or scratch...
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Human respiratory syncytial virus (RSV) is a widespread pathogen that primarily targets infants and young children but also poses a serious health risk to elderly and immunocompromised individuals. Belonging to the Pneumoviridae family, RSV is a negative-sense, single-stranded RNA virus within the Pneumovirus genus. Its global health burden is significant, with millions of cases annually resulting in hospitalizations and mortality, particularly in resource-limited settings. Although most...
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Poliomyelitis is caused by poliovirus, a small, non-enveloped, positive-sense RNA virus of the Picornaviridae family and Enterovirus genus. Transmission occurs primarily via the fecal-oral route, often through ingestion of contaminated water or food. The virus initially replicates in the oropharynx and intestinal mucosa, particularly in lymphoid tissues such as the tonsils, Peyer’s patches, and regional lymph nodes. Primary viremia follows, allowing dissemination throughout the body.In most...
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Ferret coronavirus-associated diseases.

Jerry Murray1, Matti Kiupel, Roger K Maes

  • 1Animal Clinic of Farmers Branch, 14021 Denton Drive, Dallas, TX 75234, USA.

The Veterinary Clinics of North America. Exotic Animal Practice
|August 5, 2010
PubMed
Summary

A new ferret coronavirus causes a systemic disease similar to feline infectious peritonitis (FIP). This article details the clinical signs, pathology, and management of this emerging ferret illness.

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Area of Science:

  • Veterinary Virology
  • Infectious Diseases

Background:

  • A novel ferret coronavirus, identified in 1993, causes epizootic catarrhal enteritis (ECE).
  • A recently identified ferret systemic coronavirus (FRSCV) causes a new disease resembling the dry form of feline infectious peritonitis (FIP).
  • This FRSCV-associated disease has been documented in both the United States and Europe.

Purpose of the Study:

  • To provide a comprehensive overview of the ferret FIP-like disease.
  • To discuss the clinical presentation, pathological findings, and pathogenesis of FRSCV infection.
  • To outline diagnostic strategies, treatment options, and preventive measures for this emerging ferret disease.

Main Methods:

  • Literature review and synthesis of existing data on ferret coronaviruses.
  • Analysis of clinical case reports and pathological findings associated with FRSCV.
  • Compilation of current knowledge on diagnosis, treatment, and prevention.

Main Results:

  • FRSCV causes a systemic illness in ferrets with clinical signs and pathology mimicking dry FIP.
  • The disease has been reported across multiple geographic locations, indicating its spread.
  • Understanding the pathogenesis is crucial for developing effective interventions.

Conclusions:

  • FRSCV represents a significant emerging pathogen in ferrets, necessitating veterinary attention.
  • Early diagnosis and appropriate management are key to improving outcomes for affected ferrets.
  • Further research into FRSCV pathogenesis and treatment is warranted to control this FIP-like disease.