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Related Experiment Videos

Developing spinal column: gadolinium-enhanced MR imaging.

G Sze1, S Bravo, P Baierl

  • 1Department of Neuroradiology, Yale University School of Medicine, New Haven, CT 06510.

Radiology
|August 1, 1991
PubMed
Summary

Magnetic resonance imaging reveals that normal bone marrow and cartilage in children

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Area of Science:

  • Pediatric Radiology
  • Neuroimaging
  • Skeletal Development

Background:

  • The developing pediatric spine exhibits unique enhancement patterns on magnetic resonance (MR) imaging.
  • Understanding these normal enhancement characteristics is crucial for accurate interpretation of pediatric spinal MR studies.

Purpose of the Study:

  • To characterize the enhancement patterns of the normally developing pediatric spinal column using MR imaging.
  • To differentiate normal enhancement from potential pathological findings in children.

Main Methods:

  • Retrospective analysis of MR images from 58 children (7 days to 9 years old).
  • Utilized a 1.5-T imager with short-repetition-time spin-echo sequences.
  • Images acquired before and after gadolinium-based contrast agent administration (0.1 mmol/kg gadopentetate dimeglumine).

Main Results:

  • Normal bone marrow enhancement was observed in all children under 7 years, most pronounced in those under 2 years.
  • Cartilage enhancement was noted in all children under 1.5 years, representing a key finding in infant spine MR.
  • Enhancement is attributed to prominent vasculature, capillary permeability, and extravascular space in pediatric bone marrow and cartilage.

Conclusions:

  • Vertebral body and cartilage enhancement are normal findings in the pediatric spine, particularly in younger children.
  • Radiologists must exercise caution when interpreting diffuse vertebral body enhancement in children, as it differs from adult pathological criteria.
  • These findings aid in the accurate diagnosis of spinal conditions in pediatric patients.

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