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Laparoscopic ovarian transposition before pelvic irradiation: a Saudi tertiary center experience
Ismail A Al-Badawi1, Murad Al-Aker, Jamal AlSubhi
1King Faisal Specialist Hospital and Research Center, Riyadh, Saudi Arabia. i_albadawi@yahoo.com
Objective:
To report the authors' experience with laparoscopic ovarian transposition and ovarian function preservation in women who require pelvic irradiation as part of their cancer therapy.
Design:
Cohort study.
Setting:
The gynecologic oncology service in a referral tertiary/quaternary medical center in Saudi Arabia.
Patients:
Twenty-three premenopausal patients treated with radiotherapy for a pelvic malignancy.
Interventions:
Laparoscopic ovarian transposition to paracolic gutters with uterine conservation.
Main Outcome Measures:
Preservation of ovarian function assessed by patients' symptoms and serum follicle-stimulating hormone level.
Results:
Bilateral laparoscopic ovarian transposition was performed in 23 patients: 15 with cervical cancer, 4 with rectal cancer, 3 with Ewing sarcoma, and 1 with Hodgkin lymphoma. No immediate intraoperative or postoperative complications were observed. Three patients were lost to follow-up. Ovarian preservation was achieved in 13 (65%) of 20 patients. Seven patients with low follicle-stimulating hormone levels had regular uterine bleeding at follow-up.
Conclusions:
Laparoscopic ovarian transposition is a safe and effective procedure for preserving ovarian function. This procedure should be considered in all premenopausal women who need to undergo pelvic irradiation as part of their cancer treatment.
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