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Surfactant Depletion Combined with Injurious Ventilation Results in a Reproducible Model of the Acute Respiratory Distress Syndrome (ARDS)
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[A suspected case of acute respiratory failure caused by ritodrine hydrochloride]

Kanako Urabe1, Hiroshi Mukae, Noriho Sakamoto

  • 1Second Department of Internal Medicine, Nagasaki University School of Medicine.

Nihon Kokyuki Gakkai Zasshi = the Journal of the Japanese Respiratory Society
|August 6, 2010
PubMed

A 36-year-old woman was admitted to the obstetric department because of possible premature labor of twins at 35 weeks. She had been treated by ritodrine hydrochloride, a tocolytic agent, for 1 week, and delivered healthy twins by cesarean operation. After the operation, she suddenly complained of dyspnea with associated hypoxemia and was admitted to our hospital. She presented with hypoxemia and was given a diagnosis of pulmonary edema. She was given a diuretic with ventilator therapy, and improved rapidly. However, an echocardiogram showed continuing left ventricular systolic dysfunction after 3 months. From these results, this case was suspected to be pulmonary edema due to ritodrin after myocardial failure, including peripartum cardiomyopathy.

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