Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Analytic methods for two-stage case-control studies and other stratified designs.

W D Flanders1, S Greenland

  • 1Department of Epidemiology and Biostatistics, Emory University School of Medicine, Atlanta, GA 30329.

Statistics in Medicine
|May 1, 1991
PubMed
Summary

Nested case-control studies, a hybrid design, offer efficiency by analyzing data in two stages. This study adapts pseudo-likelihood methods to fully utilize all available information in these complex epidemiological designs.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Recent Single-Family Home Buyer Knowledge, Attitudes, and Behaviors Related to Lead and Radon Exposure Prevention.

Journal of public health management and practice : JPHMP·2024
Same author

The Effect of a Regimen of Antifungal Cream Use on Episodes of Acute Adenolymphangitis (ADL) among Lymphedema Patients: An Application Using Marginal Structural Models.

Journal of epidemiology and global health·2019
Same author

Test-Retest Reproducibility of Adult-Reported High School Diet Varies among Racially and Ethnically Diverse US Men and Women.

The Journal of nutrition·2018
Same author

Cancer deaths and cases attributable to lifestyle factors and infections in China, 2013.

Annals of oncology : official journal of the European Society for Medical Oncology·2017
Same author

Norovirus in symptomatic and asymptomatic individuals: cytokines and viral shedding.

Clinical and experimental immunology·2016
Same author

Human norovirus infection and the acute serum cytokine response.

Clinical and experimental immunology·2015

Area of Science:

  • Epidemiology
  • Biostatistics

Background:

  • Nested case-control studies combine cohort and case-control study advantages.
  • Traditional analyses of two-stage case-control studies may overlook valuable data.

Purpose of the Study:

  • To adapt pseudo-likelihood analyses for two-stage case-control studies.
  • To ensure comprehensive data utilization in nested case-control designs.

Main Methods:

  • Adaptation of pseudo-likelihood methods by Kalbfleisch and Lawless (1988).
  • Application to two-stage case-control study data structures.

Main Results:

  • Demonstrates a method to incorporate all available information.
  • Provides a framework for more efficient analysis of nested case-control data.

Related Experiment Videos

Conclusions:

  • Pseudo-likelihood methods can be effectively adapted for two-stage case-control studies.
  • This approach enhances the analytical power of nested case-control designs by leveraging all data.