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Related Concept Videos

Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption01:22

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Absorption

As individuals age, their body's physiology evolves, affecting drug pharmacokinetics. The most apparent changes occur in the gastrointestinal tract, where an increase in gastric pH, a delay in gastric emptying, and a reduction in gastrointestinal motility are observed. Remarkably, these changes do not substantially modify the absorption of orally administered drugs, particularly those absorbed via passive diffusion.Transdermal drug delivery emerges as a highly viable method for older adults due...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications

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Related Experiment Video

Updated: Jun 10, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

[Therapeutic adherence in elderly].

J Petermans1, A Samalea Suarez, T Van Hees

  • 1Service de Gériatrie, CHU de Liège, Belgique. jean.petermans@chu.ulg.ac.be

Revue Medicale De Liege
|August 6, 2010
PubMed
Summary
This summary is machine-generated.

Poor therapeutic adherence is common in older adults, impacting their health and care costs. Improving patient adherence requires a focus on therapeutic education and involving patients in their treatment plans.

Related Experiment Videos

Last Updated: Jun 10, 2026

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit
06:52

Assessment of Dependence in Activities of Daily Living Among Older Patients in an Acute Care Unit

Published on: September 30, 2020

Area of Science:

  • Geriatric Medicine
  • Pharmacology
  • Patient Adherence Research

Context:

  • Therapeutic adherence, the concordance between patient behavior and medical advice, is crucial for treatment efficacy.
  • Non-adherence is particularly prevalent among geriatric patients, posing significant challenges.
  • Factors beyond patient behavior, including prescribers and drug distributors, influence adherence.

Purpose:

  • To highlight the importance of therapeutic adherence in geriatric care.
  • To emphasize the need for comprehensive strategies addressing patient adherence.
  • To advocate for the development and implementation of therapeutic education programs.

Summary:

  • Bad therapeutic adherence in geriatric patients leads to iatrogenic consequences, affecting patient functionality and increasing healthcare costs.
  • Addressing adherence requires a multi-faceted approach, focusing on patient behavior, healthcare providers, and systemic factors.
  • Therapeutic education is proposed as a standardized method to empower patients in managing their treatments, necessitating clear aims and resource allocation.

Impact:

  • Reducing poor adherence can significantly improve the quality of life for elderly individuals.
  • Optimizing therapeutic adherence can lead to substantial cost savings and improved healthcare system organization.
  • Implementing effective therapeutic education programs can enhance patient self-management and treatment outcomes.