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Updated: Jun 10, 2026

Micro-Colony Forming Unit Assay for Efficacy Evaluation of Vaccines Against Tuberculosis
Published on: July 28, 2023
[Tuberculosis control programme in Tunisia: efficacy assessment]
Mohamed Kouni Chahed1, Hédia Bellali, Sassia Dhouibi
1Département d'épidémiologie et de médecine préventive Faculté de médecine de Tunis 15, rue Djebel-Lakhda La Rabta 1007 Tunis Tunisie. mohamed.chahel@rns.tn
Abstract:
The aim of this study was to assess the efficacy of the national Tuberculosis Control Programme in Tunisia, by applying the 8-stage model proposed by Piot (1967). Two retrospective cohorts of tuberculosis cases, including all new smear-positive cases detected by all laboratories in the study area during the study period, were selected at least 2 years after treatment began. The real number of new active cases during the study period was estimated at 142, the case detection rate at 61%. In all, 70% of patients started tuberculosis treatment, and regular use of the home treatment varied from 87% (including irregular use) to 71% (excluding irregular use). The low global efficacy of the program, which ranged from 26 to 31%, indicates the need for improved application of the strategy by programme managers.
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