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Long-term restriction by APOBEC3F selects human immunodeficiency virus type 1 variants with restored Vif function

John S Albin1, Guylaine Haché, Judd F Hultquist

  • 1Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA.

Journal of Virology
|August 6, 2010
PubMed
Summary

Human immunodeficiency virus type 1 (HIV-1) Vif protein evolves distinct strategies to overcome APOBEC3F and APOBEC3G restriction factors, highlighting their differing impacts on viral replication.

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