Related Experiment Video
Updated: Jun 10, 2026

Microscopic Electric Rotary Grinding of Plaques Combined with Graft Repair in the Management of Peyronie's Disease
Published on: March 15, 2024
Evolution in the concept of erection anatomy
Ayman Awad1, Bayan Alsaid, Thomas Bessede
1Laboratory of Experimental Surgery, UPRES 4122, Faculty of Medicine, University Paris-Sud, Le Kremlin Bicêtre, France. awadayman@hotmail.com
Understanding penile anatomy and physiology is crucial for treating erectile dysfunction (ED). Precise knowledge of vascularization and innervation aids in managing ED, particularly after radical prostatectomy (RP).
Area of Science:
- Urology
- Andrology
- Neuroscience
Background:
- The anatomy and physiology of penile erection have been extensively studied over the past three decades.
- Erectile function is a complex interplay of vascular, neural, and hormonal systems.
Purpose of the Study:
- To review and summarize the existing literature on the anatomy and physiology of erection.
- To highlight key findings, particularly those from our institution's research.
Main Methods:
- A comprehensive literature search was conducted using PubMed.
- Keywords included "erection," "anatomy," and "erectile dysfunction (ED)."
- Relevant articles were critically reviewed, analyzed, and synthesized.
Main Results:
- Penile vascularization exhibits significant variability, with the internal pudendal artery being the primary blood source.
- Accessory pudendal arteries, if damaged during radical prostatectomy (RP), can impact postoperative erectile function.
- The cavernous nerves (CNs) transmit crucial neurotransmitters, including nitric oxide, which mediate erection.
- Central control of erection involves key brain structures like the medial preoptic area and paraventricular nucleus.
Conclusions:
- The surgical and functional anatomy underlying penile erection is intricate.
- A thorough understanding of penile vascularization and innervation is essential for effective ED treatment, especially post-RP.
Related Concept Videos
Male Sexual Response: Erection & Ejaculation
The blood filling the erectile tissues compresses the veins, which helps to prevent blood from leaving...
Penis
Anatomy of the Penis
The glans penis, or the head, is the terminal part of the penis and houses the external urethral orifice, the exit point for urine and semen. Covered by the prepuce, or foreskin, the glans is noted for its sensitivity and plays a key role in sexual pleasure. The body of the...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra. Symptoms...
Criticisms of the Evolutionary Perspective
Evolutionary psychology provides one explanation for these findings, suggesting...
Urethra
The anatomy of the urethra differs between males and females. In females, the urethra is short, measuring about 3–4 cm in length, and opens anterior to the vaginal opening. In males, the urethra is longer and passes through the penis, serving dual purposes: expelling urine and ejaculating semen. The male urethra is...
Development of the Sexual Organs in the Embryo and Fetus
Near the gonadal ridges, two duct systems are present: the mesonephric ducts (Wolffian ducts) and paramesonephric ducts (Müllerian ducts). These ducts form the basis for the male...