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Updated: Jun 10, 2026
Magnetic Isolation of Microglial Cells from Neonate Mouse for Primary Cell Cultures
Published on: July 25, 2022
[Influence of native bacterial magnetic particles on mouse immune response]
Chen Meng1, Jiesheng Tian, Ying Li
1State Key Laboratory for Agro-Biotechnology, Department of Microbiology and Immunology, College of Biological Science, China Agricultural University, Beijing 100193, China. mengchen2884@yahoo.com.cn
Objective:
To study the influence of native bacterial magnetic particles on mouse immune response.
Methods:
Ovalbumin was used as an antigen, mixed with complete Freund's adjuvant, bacterial magnetic particles (BMP) and phosphate buffer solution, to immunize BALB/C mouse. After 14 days later, we detected the titers of the antiovalbumin (IgG) and subtype (IgG1, IgG2a) , the proliferation ability of T lymphocyte, and the expression of IL-2, IL4, IL-10 and IFN-gamma.
Results:
Compared to the negative control group, the BMP group had the similar level in the titer of specific antibody, the proliferation ability of T lymphocyte and the expression of cytokines (IL-2, IL-4, IL-10 and IFN-gamma).
Conclusion:
Native BMPs has no significantly influence on mouse immune response.
