Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Drug Therapy01:28

Drug Therapy

The advent of drug therapy has profoundly shaped modern mental health care, providing targeted treatments for a range of psychological disorders. Psychotherapeutic drugs, classified into antianxiety, antidepressant, and antipsychotic medications, address symptoms across anxiety disorders, mood disorders, and schizophrenia. While these medications have transformed patient outcomes, they require careful management due to their potential side effects and limitations.
Antianxiety Medications
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Dosage Regimens: Designs and Approaches01:28

Dosage Regimens: Designs and Approaches

Designing a dosage regimen, which refers to the manner of drug administration, is a complex process involving the selection of drug dose, route, and frequency. This process is underpinned by pharmacokinetic parameters derived from tests and population averages. These parameters are then tailored to patient-specific variables such as diagnosis, demographics, and allergy status. Once therapy commences, therapeutic response monitoring is critical and achieved through clinical and physical...
Factors Affecting Drug Response: Overview01:21

Factors Affecting Drug Response: Overview

When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
Drug Dosage Regimen: Overview01:15

Drug Dosage Regimen: Overview

A drug dosage regimen describes the specific instructions and schedule for administering a drug to a patient. It considers factors such as drug dosage, frequency, route of administration, and duration of treatment. Designing an appropriate dosage regimen for a patient aims to achieve a target drug concentration at the site of action.
Typically, the starting dose and dosing interval are guided by the manufacturer's recommendations based on clinical trials conducted during and after drug...
Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment01:08

Effect of Hepatic Disease on Pharmacokinetics: Dose Adjustments Due to Hepatic Impairment

Hepatic impairment, characterized by decreased liver function, does not uniformly mandate adjustments in drug dosage. Whether dosage modifications are necessary depends on various factors related to the drug's metabolism and elimination pathways. If a drug is primarily excreted via the kidneys and bypasses significant hepatic processing, if it undergoes minimal metabolic transformation in the liver, or if it is volatile and primarily expelled through the lungs, dose adjustments may not be...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A comparison study between the Hemorrhage-Arresting Lever-Operated (HALO) tourniquet and the Combat Action Tourniquet (CAT) for the management of exsanguinating extremity hemorrhage.

American journal of disaster medicine·2025
Same author

Prehospital Hypertonic Saline Administration After Severe Traumatic Brain Injury.

Air medical journal·2022
Same author

Patient Care Alterations After Point-of-Care Laboratory Testing During Critical Care Transport.

Air medical journal·2022
Same author

Spine Injury for the Prehospital Provider Spinal cord injuries range from simple contusions to complete cord transection.

EMS world·2018
Same author

Talladega EMS: Behind the Scenes at NASCAR's Most Fabled Superspeedway.

EMS world·2018
Same author

Cirrhosis and Its Complications. Catch this liver scarring problem early, because its effects can be life-threatening.

EMS world·2015

Related Experiment Video

Updated: Jun 10, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Medication considerations.

Kevin T Collopy1

  • 1Spirit Ministry Medical Transpotation, Central Wisconsin, USA. kcollopy@colgatealumni.org

EMS Magazine
|August 7, 2010
PubMed
Summary

Elderly patients require adjusted drug dosages due to slower metabolism. Pregnant women must consider fetal exposure, referencing FDA guidelines before medication administration.

Area of Science:

  • Geriatric Pharmacology
  • Reproductive Toxicology

Background:

  • Elderly individuals exhibit reduced drug metabolism and elimination.
  • Medications administered to pregnant women cross the placental barrier, exposing the fetus.

Purpose of the Study:

  • To highlight the importance of dose adjustment in geriatric patients.
  • To emphasize fetal safety considerations for drug administration in pregnant women.

Main Methods:

  • Review of pharmacokinetic principles in geriatric populations.
  • Analysis of FDA drug categorization for use in pregnancy.

Main Results:

  • Geriatric patients may require lower drug doses at longer intervals.
  • Strict adherence to FDA guidelines is crucial for maternal and fetal drug safety.

More Related Videos

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Related Experiment Videos

Last Updated: Jun 10, 2026

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings
06:59

A Novel Approach for the Administration of Medications and Fluids in Emergency Scenarios and Settings

Published on: November 9, 2016

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Conclusions:

  • Pharmacotherapy in the elderly necessitates individualized dosing strategies.
  • Informed decisions regarding medication for pregnant women are vital to prevent adverse fetal outcomes.