Related Experiment Video
Updated: Jun 10, 2026

NF-κB-dependent Luciferase Activation and Quantification of Gene Expression in Salmonella Infected Tissue Culture Cells
Published on: January 12, 2020
The role of nuclear factor-kappaB in inflammatory lung disease
Abbas Ali Imanifooladi1, Samaneh Yazdani, Mohammad Reza Nourani
1Research Center of Molecular Biology, Baqiyatallah Medical Sciences University, Tehran, Iran.
Abstract:
Nuclear factor-kappaB (NF-kappaB) is one of the most important transcription factors; it has a key role in inflammatory and immune responses, cell adhesion, developmental signals, and anti-apoptosis process. Inflammatory lung diseases such as asthma and chronic obstructive pulmonary disease (COPD) are major causes of morbidity and mortality worldwide. In this review, we highlight the role of NF-kappaB in inflammatory lung disease, the strategies which block the activation of NF-kappaB, and the therapeutic approaches to treating inflammatory lung disease.
More Related Videos
Related Concept Videos
NF-κB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
NF-kB-dependent Signaling Pathway
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
Inflammatory Bowel Disease III: Crohn's Disease
Co-activators and Co-repressors
Chronic Inflammation: Introduction
Inflammatory Bowel Disease II: Ulcerative Colitis

