Related Experiment Video
Updated: Jun 10, 2026
Models of Bone Metastasis
Published on: September 4, 2012
[Metastatic calcification detected on bone scintigraphy]
Hélder Fernandes1, José Pedro Patrício, Patrícia Oliveira
1Serviço de Medicina Nuclear, Hospital S. João, Porto.
Purpose:
To show the value of bone scintigraphy in the diagnosis of metastatic calcification in end-stage renal insufficiency.
Material And Methods:
The authors present a fifty-one-year-old male with terminal renal insufficiency of hypertensive renovascular etiology, on hemodialysis for the last 10 years, referred for a bone scan because of osteoarticular complaints, and no other associated symptoms or findings on physical examination.
Results:
Whole body bone scintigraphy images (HMDP-99mTc, 925MBq), showed increased uptake in the lower half of both lungs, the stomach and renal parenchyma, compatible with metastatic calcification.
Conclusions:
Bone scintigraphy, due to its high sensitivity, even in the detection of early changes, might be a useful instrument in the initial evaluation and follow-up of patients with high risk of developing metastatic calcification.
